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Similar improvements in functional and histological healing have been reported across independent rat ligament- and muscle-injury models, synthesized in a 2025 systematic review

This insight comes from in vitro studies, which means studies done on cells isolated outside of the body (imagine scientists looking under a microscope at a petri dish)

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We identified 7 differentially methylated CpGs (FDR 0.01) in over 5% of the samples, 2) overlapped with a SNP at the measured or extension site or 3) cross-hybridized to other genomic locations

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